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La coactivacin de receptores GIP y GLP-1 tiene el potencial de intensificar estos efectos mediante mecanismos metablicos complementarios: mientras GLP-1 favorece la saciedad, la ralentizacin gstrica y la mejora de la secrecin de insulina en respuesta a nutrimentos, el GIP puede potenciar la accin teraputica al influir en la secrecin de insulina dependiente de glucosa y en la regulacin del tejido adiposo

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Sci Transl Med 6(263):263ra158-263ra158 Wu Q, Zhang Y, Zhang Y, Xia C, Lai Q, Dong Z et al (2020) Potential effects of antibiotic-induced gut microbiome alteration on bloodbrain barrier permeability compromise in rhesus monkeys

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4.2.3 A review of findings for the secondary outcomes In the non-parametric Mann Whitney U test, five biomarkers showed a marked difference with the DCM-induced animals displaying a significant increase or decrease reflecting the pathophysiological status of the rodent model used

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Most states set the legal limit of BAC at .08% for both males and females

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